Comprehensive review on repurposing of approved medicine in the management of COVID-19 infection

The SARS-CoV-2 virus, accountable for the COVID-19 pandemic, is now sweeping the globe. As a result, as this disease resists testing and adoption of new treatments, repositioning existing medications may provide a quick and appealing method with established safety, features, and dose used. They are not, however, specific or focused. However, numerous medications have been studied for their efficacy and safety in treatment of COVID-19, with the majority currently undergoing clinical trials. The goal is to rapidly expand novel preventative and therapeutic medications, as well as to apply preventive methods such as early patient identification, isolation, and treatment. Moreover, reducing transmission through physical contact is also important. In the fight against this dangerous disease, finding the proper treatment is crucial. This article summarizes several anti-malarial, anti-parasitic, monoclonal antibodies, immunosuppressant, and immunomodulating agents in clinical trials for COVID-19. The purpose of this article is to evaluate and explore the potential roles of several medications now utilized in COVID-19.

Understanding the COVID-19 prevention and control strategies and their appropriate applicability through the basics of epidemiology

The current article is about the background knowledge of corona, various epidemiological definitions and different strategies adopted to prevent and control corona infection. How the preventive measures are applied and what is epidemiological basis behind these measures is the core of the article. The article also mentioned the variations in mortality pattern and goes on defining important indicators as case-fatality ratio, deaths/1 lakh population and the relevance of both in the current situation of corona infection. In the article, important terms such as different types of cases in corona infection, basic reproduction number, effective reproduction number, and their epidemiological significance in corona infection, herd immunity, and herd immunity threshold are discussed. The importance of lockdown as a preventive measure, enforcement of epidemic disease act 1897 and its amendment, disaster management act 2005, social distancing, cough etiquette, and others are highlighted.